Brian uses structural bioinformatics approaches to explore spatial and energetic patterns in protein:protein interactions. He is currently a member of the Life Sciences and Jetstream Cloud Computing Groups at TACC, after previously creating and managing the Nevada Center for Bioinformatics and later working as a Computational Biology professor at Texas Woman's University. He is based out of the Dallas/Fort Worth metroplex with the goal of supporting computational biology, bioinformatics, and cloud computing research in DFW metroplex UT institutions.